An interpenetrated bioactive nonlinear optical MOF containing a coordinated quinolone-like drug and Zn(ii) for pH-responsive releaseElectronic supplementary information (ESI) available. CCDC 1004090. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4dt02672a

A new interpenetrated bioactive nonlinear optical metal-organic framework [Zn 2 (ppa) 2 (1,3-bdc)(H 2 O)] has been designed and synthesized, which shows both a high drug content of 63.9% and a good slow release effect in simulated physical conditions compared to other non-interpenetrated bioactive M...

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Main Authors: Duan, Li-Na, Dang, Qin-Qin, Han, Cai-Yun, Zhang, Xian-Ming
Format: Article
Language:English
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Summary:A new interpenetrated bioactive nonlinear optical metal-organic framework [Zn 2 (ppa) 2 (1,3-bdc)(H 2 O)] has been designed and synthesized, which shows both a high drug content of 63.9% and a good slow release effect in simulated physical conditions compared to other non-interpenetrated bioactive MOFs. It also shows a large powder second-harmonic generation (SHG) efficiency of 5.6 times that of KH 2 PO 4 (particle size: 150-200 μm). An interpenetrated acentric bioactive MOF with a high drug content of 63.9% has been prepared, which shows a good release of the drug and a strong SHG signal.
ISSN:1477-9226
1477-9234
DOI:10.1039/c4dt02672a