Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffoldElectronic supplementary information (ESI) available: Synthetic procedures, characterization data (1H and 13C NMR, IR, and HRMS), sigmoidal curves derived from UV/Vis equilibration assay, rate determination assay plots, and procedure and plots for DMSO titration studies. See DOI: 10.1039/c4ob00398e

The effect of aryl substitution on various aspects of the interconversion of ortho -hydroxychalcones and flavanones has been studied using multiple spectroscopic techniques. Derivatization of the core scaffold predictably alters the midpoint pH of this equilibration process suggesting its viability...

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Main Authors: Muller, Brian M, Mai, Jesse, Yocum, Reid A, Adler, Marc J
Format: Article
Language:English
Online Access:Get full text
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Summary:The effect of aryl substitution on various aspects of the interconversion of ortho -hydroxychalcones and flavanones has been studied using multiple spectroscopic techniques. Derivatization of the core scaffold predictably alters the midpoint pH of this equilibration process suggesting its viability for application as a functional colorimetric molecular switch. The impact of substitution on a novel colorimetric dynamic covalent switching scaffold was investigated using UV/Vis and NMR spectroscopy.
ISSN:1477-0520
1477-0539
DOI:10.1039/c4ob00398e