A general catalyst for Suzuki-Miyaura and Sonogashira reactions of aryl and heteroaryl chlorides in waterElectronic supplementary information (ESI) available. See DOI: 10.1039/c4ob00846d

We report the synthesis of 2-(3-sulfonatomesityl)-5-sulfonatoindenyl)dicyclohexylphosphine hydrate sodium salt and its use in palladium-catalyzed Suzuki-Miyaura and Sonogashira coupling reactions in water (and biphasic water-organic solvent mixtures) to prepare a variety of functionalized biaryls an...

Full description

Saved in:
Bibliographic Details
Main Authors: Peng, Hui, Chen, Ya-Qin, Mao, Shu-Lan, Pi, Yun-Xiao, Chen, You, Lian, Ze-Yu, Meng, Tong, Liu, Sheng-Hua, Yu, Guang-Ao
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report the synthesis of 2-(3-sulfonatomesityl)-5-sulfonatoindenyl)dicyclohexylphosphine hydrate sodium salt and its use in palladium-catalyzed Suzuki-Miyaura and Sonogashira coupling reactions in water (and biphasic water-organic solvent mixtures) to prepare a variety of functionalized biaryls and aryl alkynes in excellent yield. An air-stable sulfonated indenyl phosphine/Pd-catalyst system was used in Suzuki-Miyaura and Sonogashira coupling reactions in water.
ISSN:1477-0520
1477-0539
DOI:10.1039/c4ob00846d