Copper(i) iodide catalyzed synthesis of primary propargylic alcohols from terminal alkyneElectronic supplementary information (ESI) available: Experimental details, MS and 1HNMR and 13CNMR for all products. See DOI: 10.1039/c4ra12719f

A highly efficient and practical method for the synthesis of primary propargylic alcohols has been developed using CuI as catalyst and paraformaldehyde as the formaldehyde source. The reaction was performed under mild reaction conditions offering the desired products in good to excellent yields with...

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Bibliographic Details
Main Authors: Kundu, Shrishnu Kumar, Mitra, Kanchan, Majee, Adinath
Format: Article
Language:English
Online Access:Get full text
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Summary:A highly efficient and practical method for the synthesis of primary propargylic alcohols has been developed using CuI as catalyst and paraformaldehyde as the formaldehyde source. The reaction was performed under mild reaction conditions offering the desired products in good to excellent yields with a variety of terminal alkynes. Synthesis of primary propargylic alcohols from terminal alkyne and paraformaldehyde catalyzed by copper( i ) iodide, without using any moisture sensitive reagents.
ISSN:2046-2069
DOI:10.1039/c4ra12719f