Electrochemical analysis of a novel ferrocene derivative as a potential antitumor drugElectronic supplementary information (ESI) available: Material, synthesis and characterization of compound 2; cell cultures; MTT assay; sample preparation; nuclear and cytoplasm fraction extraction; electrochemical measurement, Fig. S1-S11. See DOI: 10.1039/c5an00958h

Ferrocenes represent an interesting group of drugs with potential antitumor properties. Moreover, their electronic properties make them suitable for electrochemical studies. We determined an uptake of a novel ferrocene derivative in low μM concentrations by selected cancer cell lines and showed its...

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Main Authors: Bartošík, M, Koubková, L, Karban, J, ervenková Š astná, L, Hodík, T, Lama, M, Pinkas, J, Hrstka, R
Format: Article
Language:English
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Summary:Ferrocenes represent an interesting group of drugs with potential antitumor properties. Moreover, their electronic properties make them suitable for electrochemical studies. We determined an uptake of a novel ferrocene derivative in low μM concentrations by selected cancer cell lines and showed its localization predominantly in cytoplasm, using glassy carbon electrodes. Ferrocenes represent an interesting group of drugs with potential antitumor properties.
ISSN:0003-2654
1364-5528
DOI:10.1039/c5an00958h