DNA-hybrid-gated functional mesoporous silica for sensitive DNA methyltransferase SERS detectionElectronic supplementary information (ESI) available. See DOI: 10.1039/c5cc05463j

Mesoporous silica nanoparticles (MSNs) were used as a nano-carrier/amplifier to develop a novel MSN-SERS probe for DNA MTase detection. High sensitivity, good selectivity, and rapid analysis are achieved. By combining mesoporous silica nanoparticles and surface-enhanced Raman scattering assisted str...

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Bibliographic Details
Main Authors: Wang, Xiaomeng, Cui, Meirong, Zhou, Hong, Zhang, Shusheng
Format: Article
Language:English
Online Access:Get full text
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Summary:Mesoporous silica nanoparticles (MSNs) were used as a nano-carrier/amplifier to develop a novel MSN-SERS probe for DNA MTase detection. High sensitivity, good selectivity, and rapid analysis are achieved. By combining mesoporous silica nanoparticles and surface-enhanced Raman scattering assisted strand-scission cycles, we developed an ultrasensitive and specific DNA methyltransferase detection method.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc05463j