A water-stable metal-organic framework of a zwitterionic carboxylate with dysprosium: a sensing platform for Ebolavirus RNA sequencesElectronic supplementary information (ESI) available: General synthesis, X-ray crystallography, crystallographic data, selected bond distances and angles, thermogravimetric analysis and the 3D structure of 1. Ebolavirus RNA detection and fluorescence anisotropy experiments. The fluorescence quenching efficiency of P-DNA by compound 1, H3CmdcpBr and Dy(NO3)3 (pH 7.4

We herein report a water-stable 3D dysprosium-based metal-organic framework (MOF) that can non-covalently interact with probe ss-DNA. The formed system can serve as an effective fluorescence sensing platform for the detection of complementary Ebolavirus RNA sequences with the detection limit of 160...

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Main Authors: Qin, Liang, Lin, Li-Xian, Fang, Zhi-Ping, Yang, Shui-Ping, Qiu, Gui-Hua, Chen, Jin-Xiang, Chen, Wen-Hua
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Summary:We herein report a water-stable 3D dysprosium-based metal-organic framework (MOF) that can non-covalently interact with probe ss-DNA. The formed system can serve as an effective fluorescence sensing platform for the detection of complementary Ebolavirus RNA sequences with the detection limit of 160 pM. A 3D Dy-based metal-organic framework (MOF) 1 was synthesized. Compound 1 can interact with the probe DNA to form a P-DNA@ 1 system. This system can be used as an effective fluorescent sensing platform for the detection of Ebolavirus RNA.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc06697b