Electrochemical primer extension for the detection of single nucleotide polymorphisms in the cardiomyopathy associated MYH7 geneElectronic supplementary information (ESI) available: Details of sequences and experimental procedures used. See DOI: 10.1039/c5cc07762a

We report the labelling of dideoxy nucleotides (ddNTPs) for use in electrochemical array based primer extension for the detection of single nucleotide polymorphisms (SNPs). The results confirm the extension of the immobilised primers for each of the four ddNTPs, representing a significant advance in...

Full description

Saved in:
Bibliographic Details
Main Authors: Debela, A. M, Thorimbert, S, Hasenknopf, B, O'Sullivan, C. K, Ortiz, M
Format: Article
Language:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report the labelling of dideoxy nucleotides (ddNTPs) for use in electrochemical array based primer extension for the detection of single nucleotide polymorphisms (SNPs). The results confirm the extension of the immobilised primers for each of the four ddNTPs, representing a significant advance in achieving a cost-effective platform for screening of disease-specific SNPs. We report the labelling of dideoxy nucleotides (ddNTPs) for use in electrochemical array based primer extension for the detection of single nucleotide polymorphisms (SNPs).
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc07762a