A novel chiral electrochemiluminescence sensor that can discriminate proline enantiomersElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ra13528a

A sensitive, stable and stereoselective electrochemiluminescence (ECL) sensor has been designed to enantioselectively discriminate proline enantiomers by immobilizing Ru(bpy) 3 2+ -gold nanoparticles (Ru-AuNPs) and β-cyclodextrin-reduced graphene oxide (β-CD-rGO) on glassy carbon electrode. More Ru(...

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Bibliographic Details
Main Authors: Wang, Qinghong, Lin, Xia, Guo, Dongmei, Xu, Juanjuan, Xuan, Chunzhi, Chen, Cui, Fu, Yingzi
Format: Article
Language:English
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Summary:A sensitive, stable and stereoselective electrochemiluminescence (ECL) sensor has been designed to enantioselectively discriminate proline enantiomers by immobilizing Ru(bpy) 3 2+ -gold nanoparticles (Ru-AuNPs) and β-cyclodextrin-reduced graphene oxide (β-CD-rGO) on glassy carbon electrode. More Ru(bpy) 3 2+ could be immobilized on the surface of electrode stably via preparing Ru-AuNPs and better stereoselectivity could be introduced to the sensor via the synthesis of β-CD-rGO. When the developed sensor interacted with proline enantiomers, obvious difference of ECL intensities towards l - and d -proline was observed, and a larger intensity was obtained from d -proline. As a result, ECL technique might act as a promising method to chiral recognition of amino acids enantiomers or chiral drugs. A chiral stereoselective electrochemiluminescence (ECL) sensor was constructed by using Ru-AuNPs and β-CD-rGO composites to discriminate proline enantiomers.
ISSN:2046-2069
DOI:10.1039/c5ra13528a