Pd/C-catalyzed facile synthesis of primary aromatic amides by aminocarbonylation of aryl iodides using ammonia surrogatesElectronic supplementary information (ESI) available: Materials and methods, experimental procedure, 1H, 13C NMR and GC-MS data of products. See DOI: 10.1039/c5ra15831a

• Main Authors: Mane, Rajendra S, Bhanage, Bhalchandra M
• Format: Article
• Language: English
• ISSN: 2046-2069
• DOI: 10.1039/c5ra15831a

Use of Pd/C as an efficient, phosphine free, heterogeneous and recyclable catalyst for one pot carbonylative synthesis of primary aromatic amides has been demonstrated. The developed protocol is simple to perform and employs ammonium carbamate as an in situ solid ammonia source which is feasible and more convenient than direct use of ammonia gas. The applicability of the developed protocol was studied for various aryl iodide substrates and it was found that it provides good to excellent yields of the desired amides. The catalyst is easily separable and shows significant recyclability for up to four consecutive cycles without loss of catalytic activity. Use of Pd/C as an efficient, phosphine free, heterogeneous and recyclable catalyst for one pot carbonylative synthesis of primary aromatic amides has been demonstrated.