A novel colorimetric and near-infrared fluorescent probe for hydrogen peroxide imaging in vitro and in vivoElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ra16827a

A novel NIR fluorescent probe (DCM-B2) based on dicyanomethylene-4 H -pyran was synthesized for the detection of H 2 O 2 . This colorimetric fluorescent probe displays a fluorescence turn-on response following the conversion of the aryl boronate unit to phenol in the presence of H 2 O 2 . It could o...

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Bibliographic Details
Main Authors: Wang, Peng, Wang, Ke, Chen, Dan, Mao, Yibo, Gu, Yueqing
Format: Article
Language:English
Online Access:Get full text
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Summary:A novel NIR fluorescent probe (DCM-B2) based on dicyanomethylene-4 H -pyran was synthesized for the detection of H 2 O 2 . This colorimetric fluorescent probe displays a fluorescence turn-on response following the conversion of the aryl boronate unit to phenol in the presence of H 2 O 2 . It could offer good performance in terms of sensitivity, selectivity, and low cytotoxicity. Furthermore, bioimaging investigations indicated that this probe was cell permeable and suitable for monitoring H 2 O 2 in vitro and in vivo . A novel NIR fluorescent probe (DCM-B2) based on dicyanomethylene-4 H -pyran was synthesized for the detection of H 2 O 2 .
ISSN:2046-2069
DOI:10.1039/c5ra16827a