An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing

This review evaluates hydrogel-forming polymers that are suitable for soft tissue engineering with a focus on materials that can be fabricated using additive manufacturing (3D-printing). An overview of the specific material requirements for hydrogel-based tissue engineering constructs is presented....

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Bibliographic Details
Published in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2015-05, Vol.3 (2), p.415-4117
Main Authors: Kirchmajer, D. M, Gorkin III, R, in het Panhuis, M
Format: Article
Language:English
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Summary:This review evaluates hydrogel-forming polymers that are suitable for soft tissue engineering with a focus on materials that can be fabricated using additive manufacturing (3D-printing). An overview of the specific material requirements for hydrogel-based tissue engineering constructs is presented. This is followed by an explanation of the various hydrogel-forming polymer classes that includes a detailed examination of material properties that are critical for extrusion printing. Specifically, mechanisms for hydrogel formation, degradation, and biological response, activity and compatibility are explored. A discussion of extrusion printing strategies for printable hydrogel-forming polymers is then presented in conjunction with a list of considerations to guide future tissue engineering developments. In this review hydrogel-forming polymers that are suitable for extrusion-based 3D printing are evaluated.
ISSN:2050-750X
2050-7518
DOI:10.1039/c5tb00393h