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Facile synthesis of magnetic core-shell nanocomposites for MRI and CT bimodal imagingElectronic supplementary information (ESI) available. See DOI: 10.1039/c5tb00775e

With the development of nanotechnology, nanocomposites have been used as bimodal contrast agents for magnetic resonance (MR) and computed tomography (CT) imaging. We have developed a facile method for the synthesis of iron oxide@bismuth sulfide magnetic core-shell nanocomposites. These bifunctional...

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Main Authors: Zhu, Jing, Wang, Jiaqing, Wang, Xin, Zhu, Jingfen, Yang, Yanmei, Tian, Jian, Cui, Wenguo, Ge, Cuicui, Li, Yonggang, Pan, Yue, Gu, Hongwei
Format: Article
Language:English
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Summary:With the development of nanotechnology, nanocomposites have been used as bimodal contrast agents for magnetic resonance (MR) and computed tomography (CT) imaging. We have developed a facile method for the synthesis of iron oxide@bismuth sulfide magnetic core-shell nanocomposites. These bifunctional nanocomposites can be made water-soluble via PEG coating and present strong MRI/CT contrast enhancement. Evaluation of cytotoxicity by MTT assay shows that the nanocomposites have low cytotoxicity. The results illustrate that the nanocomposites have great potential as bimodal imaging agents for MR/CT. A facile synthesis of nanocomposites for MR/CT bimodal imaging with a magnetic iron oxide core and bismuth-based shell.
ISSN:2050-750X
2050-7518
DOI:10.1039/c5tb00775e