Tetrameric psuedo-peptide receptors with allosteric properties

This paper reports the binding properties of tetrameric pseudo-peptide receptors for protonated cytidines. The receptors, which were isolated from a dynamic combinatorial chemistry (DCC) experiment, bind the analytes with affinities that depend on the presence or absence of excess acid, and with a s...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2016-06, Vol.52 (52), p.813-816
Main Authors: Chung, Mee-Kyung, Lee, Stephen J, Waters, Marcey L, Gagné, Michel R
Format: Article
Language:English
Subjects:
Affinity
Binding
Combinatorial chemistry
Dynamic tests
Dynamics
Receptors
Stoichiometry
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Summary:This paper reports the binding properties of tetrameric pseudo-peptide receptors for protonated cytidines. The receptors, which were isolated from a dynamic combinatorial chemistry (DCC) experiment, bind the analytes with affinities that depend on the presence or absence of excess acid, and with a stoichiometry that is both concentration and temperature dependent. This paper reports the binding properties of tetrameric pseudo-peptide receptors for protonated cytidines.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc03296f