A new way to do an old reaction: highly efficient reduction of organic azides by sodium iodide in the presence of acidic ion exchange resinElectronic supplementary information (ESI) available: Full experimental details, including full compound characterization and spectra. See DOI: 10.1039/c6cc08574a

Organic azides are readily reduced to the corresponding amines by treatment with sodium iodide in the presence of acidic ion exchange resin. The process, optimal when performed at 40 °C and 200 mbar pressure on a rotatory evaporator, is extremely efficient, clean, and tolerant of a variety of functi...

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Main Authors: Suthagar, Kajitha, Fairbanks, Antony J
Format: Article
Language:English
Online Access:Get full text
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Summary:Organic azides are readily reduced to the corresponding amines by treatment with sodium iodide in the presence of acidic ion exchange resin. The process, optimal when performed at 40 °C and 200 mbar pressure on a rotatory evaporator, is extremely efficient, clean, and tolerant of a variety of functional groups. Azides are reduced highly efficiently simply by treatment with sodium iodide in the presence of acidic ion exchange resin.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc08574a