Iodinated cyanine dyes: a new class of sensitisers for use in NIR activated photodynamic therapy (PDT)Electronic supplementary information (ESI) available: Synthetic and experimental procedures. See DOI: 10.1039/c6cc09624g

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in two pancreatic cell lines as well as excellent tumour control in a murine model of the disease. Iodinated cyanine dye 6a has been developed for use as a NI...

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Main Authors: Atchison, Jordan, Kamila, Sukanta, Nesbitt, Heather, Logan, Kieran A, Nicholas, Dean M, Fowley, Colin, Davis, James, Callan, Bridgeen, McHale, Anthony P, Callan, John F
Format: Article
Language:English
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Summary:A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in two pancreatic cell lines as well as excellent tumour control in a murine model of the disease. Iodinated cyanine dye 6a has been developed for use as a NIR excited photosensitiser in photodynamic therapy.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc09624g