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Layer-by-layer assembly of hemoglobin-coated microspheres for enhancing the oxygen carrying capacity

Hemoglobin-coated microspheres with one layer and five layers were fabricated by layer-by-layer assembly. The electrochemical methods were used to study their capacity for carrying oxygen. The results provided direct evidences that microspheres with five-layer hemoglobin could store and release more...

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Bibliographic Details
Published in:RSC advances 2016-01, Vol.6 (65), p.59984-59987
Main Authors: Sun, Lijun, Lu, Yannan, Pan, Zhongqin, Wu, Tingting, Liu, Xiaojun, Bao, Ning, Yu, Chunmei, He, Hong, Gu, Haiying
Format: Article
Language:English
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Summary:Hemoglobin-coated microspheres with one layer and five layers were fabricated by layer-by-layer assembly. The electrochemical methods were used to study their capacity for carrying oxygen. The results provided direct evidences that microspheres with five-layer hemoglobin could store and release more oxygen than those with one layer. This study also provided an alternative method for evaluating the oxygen carrying capacity of hemoglobin microspheres. Hemoglobin-coated microspheres with one layer and five layers were fabricated by layer-by-layer assembly.
ISSN:2046-2069
2046-2069
DOI:10.1039/c6ra05638e