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Kinetics and mechanism of degradation of chitosan by combining sonolysis with HO/ascorbic acid

This study demonstrated the combined use of sonolysis with the H 2 O 2 /ascorbic acid (Vc) redox reaction to degrade chitosan (CS). The influence of operating parameters, such as the initial CS concentration (1-15 mg mL −1 ), the input power level (15-45% of the total input power), the H 2 O 2 and V...

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Bibliographic Details
Published in:RSC advances 2016-08, Vol.6 (8), p.7628-76287
Main Authors: Wu, Tiantian, Wu, Chunhua, Xiang, Yingchun, Huang, Jiaqi, Luan, Lanlan, Chen, Shiguo, Hu, Yaqin
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Summary:This study demonstrated the combined use of sonolysis with the H 2 O 2 /ascorbic acid (Vc) redox reaction to degrade chitosan (CS). The influence of operating parameters, such as the initial CS concentration (1-15 mg mL −1 ), the input power level (15-45% of the total input power), the H 2 O 2 and Vc concentration (10-70 mM) and the pH (3.0-5.0) of the reaction solution, on the molecular weight and degradation kinetics of CS were investigated and optimized. Based on the degradation kinetics, a synergetic effect of sonolysis with H 2 O 2 and Vc on the degradation of CS was observed. Structural analysis by FT-IR and 1 H and 13 C NMR indicated no significant difference between the chemical structure of chitosan before and after degradation. Moreover, intermolecular hydrogen bonds were broken, and the crystallinity of degraded chitosan decreased. Using the above analysis, CS degradation by the combination of sonolysis with the H 2 O 2 /Vc redox reaction was proposed to be due to mechanical effects along with HO&z.rad; attack on the β-1,4-glucoside linkages of glucosamine units. These results suggest that the sonolysis/H 2 O 2 /Vc combined technique is promisingly suitable for large-scale manufacture of chitooligosaccharide. This study demonstrated the combined use of sonolysis with the H 2 O 2 /ascorbic acid (Vc) redox reaction to degrade chitosan (CS).
ISSN:2046-2069
DOI:10.1039/c6ra11197a