Convenient and efficient synthesis of functionalized unsymmetrical alkynyl sulfidesElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra19440k

We developed a simple and efficient method for the synthesis of functionalized unsymmetrical alkynyl sulfides under mild conditions in good yields. The designed method is based on the reaction of 5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-disulfanyl derivatives with lithium acetylides. The deve...

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Bibliographic Details
Main Authors: Doroszuk, J, Musiejuk, M, Demkowicz, S, Rachon, J, Witt, D
Format: Article
Language:English
Online Access:Get full text
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Summary:We developed a simple and efficient method for the synthesis of functionalized unsymmetrical alkynyl sulfides under mild conditions in good yields. The designed method is based on the reaction of 5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-disulfanyl derivatives with lithium acetylides. The developed method allows the preparation of unsymmetrical alkynyl sulfides bearing additional hydroxyl, carboxyl, or amino functionalities. We developed a simple and efficient method for the synthesis of functionalized unsymmetrical alkynyl sulfides under mild conditions in good yields.
ISSN:2046-2069
DOI:10.1039/c6ra19440k