An electrochemiluminescence biosensor for Kras mutations based on locked nucleic acid functionalized DNA walkers and hyperbranched rolling circle amplificationElectronic supplementary information (ESI) available: Experimental details and data. See DOI: 10.1039/c7cc00009j

Herein, an electrochemiluminescence (ECL) biosensor for ultrasensitive and specific detection of Kras mutant genes has been developed on the basis of the high discrimination capability of locked nucleic acid (LNA) and dual signal amplification techniques including DNA walkers and hyperbranched rolli...

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Main Authors: Zhang, Ying, Wang, Lixu, Luo, Fang, Qiu, Bin, Guo, Longhua, Weng, Zuquan, Lin, Zhenyu, Chen, Guonan
Format: Article
Language:English
Online Access:Get full text
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Summary:Herein, an electrochemiluminescence (ECL) biosensor for ultrasensitive and specific detection of Kras mutant genes has been developed on the basis of the high discrimination capability of locked nucleic acid (LNA) and dual signal amplification techniques including DNA walkers and hyperbranched rolling circle amplification (HRCA). Herein, an electrochemiluminescence (ECL) biosensor for ultrasensitive and specific detection of Kras mutant genes has been developed.
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc00009j