A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopyElectronic supplementary information (ESI) available: Synthetic procedures and characterization of the new compounds, and widefield and super-resolution microscopy details. See DOI: 10.1039/c7cc04996j

A new photoactivatable fluorophore based on a quinone-cyanine-7 (QCy7) scaffold was synthesized and spectroscopically characterized. The fluorophore exhibits fluorescence in the near-infrared spectral window and a large Stokes shift. Its application in super-resolution microscopy as an antibody bioc...

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Bibliographic Details
Main Authors: Klötzner, Dean-Paulos, Klehs, Kathrin, Heilemann, Mike, Heckel, Alexander
Format: Article
Language:English
Online Access:Get full text
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Summary:A new photoactivatable fluorophore based on a quinone-cyanine-7 (QCy7) scaffold was synthesized and spectroscopically characterized. The fluorophore exhibits fluorescence in the near-infrared spectral window and a large Stokes shift. Its application in super-resolution microscopy as an antibody bioconjugate is demonstrated. In this work we present a new photoactivatable QCy7-based fluorophore and demonstrate its application in single-molecule super-resolution microscopy.
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc04996j