"A Jack of Trio"-robust one-pot metal free oxidative amination, azidation and peroxidation of phenolsElectronic supplementary information (ESI) available: Copies of 1H and 13C spectra. See DOI: 10.1039/c7nj00169j

Herein we disclose a highly efficient methodology for the generation of nitrogen containing quaternary carbon centres via aminative and azidative oxidative dearomatization of phenols. The same protocol has also been successfully employed to achieve oxidative peroxidation of phenols. The simplest met...

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Bibliographic Details
Main Authors: Sarkar, Debayan, Ghosh, Manoj Kumar, Rout, Nilendri, Kuila, Puspendu
Format: Article
Language:English
Online Access:Get full text
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Summary:Herein we disclose a highly efficient methodology for the generation of nitrogen containing quaternary carbon centres via aminative and azidative oxidative dearomatization of phenols. The same protocol has also been successfully employed to achieve oxidative peroxidation of phenols. The simplest metal free reaction conditions delineate an easy breakthrough to the " Trio "- oxidative amination, azidation and peroxidation. An array of diverse polyfunctionalised heterocycles has been synthesized in one pot. Facile generation of quaternary carbon centres has been realised in the presence of phenyl trimethyl ammonium tribromide (PTAB) mediated oxidative dearomatisation.
ISSN:1144-0546
1369-9261
DOI:10.1039/c7nj00169j