Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base-Ru(ii)-curcumin organometallic conjugateElectronic supplementary information (ESI) available: Experimental details, photophysics, biological, computational details and crystallographic details. CCDC 1588180 (TB-1) and 1823765 (TB-Ru-Cur). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8cc01584h

The synthesis, photophysics and biological investigation of fluorescent 4-amino-1,8-naphthalimide Tröger's bases ( TB-1-TB-3 ) and a new Tröger's base p -cymene-Ru( ii )-curcumin organometallic conjugate ( TB-Ru-Cur ) are described; these compounds showed fast cellular uptake and displayed...

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Main Authors: Shanmugaraju, Sankarasekaran, la Cour Poulsen, Bjørn, Arisa, Tobi, Umadevi, Deivasigamani, Dalton, Hannah L, Hawes, Chris S, Estalayo-Adrián, Sandra, Savyasachi, Aramballi J, Watson, Graeme W, Williams, D. Clive, Gunnlaugsson, Thorfinnur
Format: Article
Language:English
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Summary:The synthesis, photophysics and biological investigation of fluorescent 4-amino-1,8-naphthalimide Tröger's bases ( TB-1-TB-3 ) and a new Tröger's base p -cymene-Ru( ii )-curcumin organometallic conjugate ( TB-Ru-Cur ) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells. Biological investigation of a new Tröger's base-Ru( ii )-curcumin conjugate is described.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc01584h