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Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base-Ru(ii)-curcumin organometallic conjugateElectronic supplementary information (ESI) available: Experimental details, photophysics, biological, computational details and crystallographic details. CCDC 1588180 (TB-1) and 1823765 (TB-Ru-Cur). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8cc01584h
The synthesis, photophysics and biological investigation of fluorescent 4-amino-1,8-naphthalimide Tröger's bases ( TB-1-TB-3 ) and a new Tröger's base p -cymene-Ru( ii )-curcumin organometallic conjugate ( TB-Ru-Cur ) are described; these compounds showed fast cellular uptake and displayed...
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creator | Shanmugaraju, Sankarasekaran la Cour Poulsen, Bjørn Arisa, Tobi Umadevi, Deivasigamani Dalton, Hannah L Hawes, Chris S Estalayo-Adrián, Sandra Savyasachi, Aramballi J Watson, Graeme W Williams, D. Clive Gunnlaugsson, Thorfinnur |
description | The synthesis, photophysics and biological investigation of fluorescent 4-amino-1,8-naphthalimide Tröger's bases (
TB-1-TB-3
) and a new Tröger's base
p
-cymene-Ru(
ii
)-curcumin organometallic conjugate (
TB-Ru-Cur
) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells.
Biological investigation of a new Tröger's base-Ru(
ii
)-curcumin conjugate is described. |
doi_str_mv | 10.1039/c8cc01584h |
format | article |
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TB-1-TB-3
) and a new Tröger's base
p
-cymene-Ru(
ii
)-curcumin organometallic conjugate (
TB-Ru-Cur
) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells.
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ii
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TB-1-TB-3
) and a new Tröger's base
p
-cymene-Ru(
ii
)-curcumin organometallic conjugate (
TB-Ru-Cur
) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells.
Biological investigation of a new Tröger's base-Ru(
ii
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TB-1-TB-3
) and a new Tröger's base
p
-cymene-Ru(
ii
)-curcumin organometallic conjugate (
TB-Ru-Cur
) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells.
Biological investigation of a new Tröger's base-Ru(
ii
)-curcumin conjugate is described.</abstract><doi>10.1039/c8cc01584h</doi><tpages>4</tpages></addata></record> |
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source | Royal Society of Chemistry:Jisc Collections:Royal Society of Chemistry Read and Publish 2022-2024 (reading list) |
title | Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base-Ru(ii)-curcumin organometallic conjugateElectronic supplementary information (ESI) available: Experimental details, photophysics, biological, computational details and crystallographic details. CCDC 1588180 (TB-1) and 1823765 (TB-Ru-Cur). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8cc01584h |
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