Visible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenesElectronic supplementary information (ESI) available: Experimental details and spectra of all new products. See DOI: 10.1039/c8cc03105c

A visible-light induced three-component reaction of difluoroalkyl halides, unactivated alkenes, and alkynyl sulfones is described, providing a direct and general approach to the construction of synthetically valuable β-difluoroalkylated alkynes under room temperature conditions. This represents the...

Full description

Saved in:
Bibliographic Details
Main Authors: Jin, Weiwei, Wu, Mingchang, Xiong, Zhimin, Zhu, Gangguo
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A visible-light induced three-component reaction of difluoroalkyl halides, unactivated alkenes, and alkynyl sulfones is described, providing a direct and general approach to the construction of synthetically valuable β-difluoroalkylated alkynes under room temperature conditions. This represents the first intermolecular alkynyl-difluoroalkylation of unactivated alkenes. A visible-light induced three-component alkynyl-fluoroalkylation of unactivated alkenes is described, giving a facile access to β-fluoroalkylated alkynes under room temperature conditions.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc03105c