Cytidine- and guanosine-based nucleotide-lipidsElectronic supplementary information (ESI) available: Synthesis and characterization data for nucleotide lipids. See DOI: 10.1039/c8ob01023d

Hybrid nucleotide-lipids composed of a lipid covalently attached to purine and pyrimidine nucleobases exhibit supramolecular properties. The novel cytidine and guanosine derivatives are promising bioinspired materials, which can act as supramolecular gelators depending on both the nucleobase and the...

Full description

Saved in:
Bibliographic Details
Main Authors: Alies, Bruno, Ouelhazi, Mohamed A, Patwa, Amit, Verget, Julien, Navailles, Laurence, Desvergnes, Valérie, Barthélémy, Philippe
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hybrid nucleotide-lipids composed of a lipid covalently attached to purine and pyrimidine nucleobases exhibit supramolecular properties. The novel cytidine and guanosine derivatives are promising bioinspired materials, which can act as supramolecular gelators depending on both the nucleobase and the presence of salts. These supramolecular properties are of broad interest for biomedical applications. A nucleotide-lipids family featuring the four natural nucleobases was explored through their self-assembly properties.
ISSN:1477-0520
1477-0539
DOI:10.1039/c8ob01023d