Loading…

Molecular recognition of organophosphorus compounds in water and inhibition of their toxicity to acetylcholinesterase

Molecular tubes with hydrogen bonding donors in their deep hydrophobic cavities are able to selectively bind organophosphorus compounds in water through hydrogen bonding and the hydrophobic effect. They can also be used as a fluorescent sensor for nerve agent simulants and as an inhibitor to reduce...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2019-08, Vol.55 (66), p.9797-98
Main Authors: Liu, Wei-Er, Chen, Zhao, Yang, Liu-Pan, Au-Yeung, Ho Yu, Jiang, Wei
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Molecular tubes with hydrogen bonding donors in their deep hydrophobic cavities are able to selectively bind organophosphorus compounds in water through hydrogen bonding and the hydrophobic effect. They can also be used as a fluorescent sensor for nerve agent simulants and as an inhibitor to reduce the toxicity of paraoxon to acetylcholinesterase. endo -Functionalized molecular tubes are able to recognize toxic organophosphorus compounds in water. They can be used as a fluorescent sensor and as an inhibitor to reduce the toxicity of paraoxon to acetylcholinesterase.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc04603h