A carbon-based polymer dot sensor for breast cancer detection using peripheral blood immunocytes

We constructed a carbon-based polymer dot (CPD) sensor to detect breast cancer based on the differences of peripheral blood cells, providing a new minimally invasive method for cancer diagnosis. This simple and extensible system exhibits clinically relevant accuracy in terms of cancer identification...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (2), p.35-353
Main Authors: Liu, Meng-Xian, Chen, Shuai, Ding, Na, Yu, Yong-Liang, Wang, Jian-Hua
Format: Article
Language:English
Subjects:
Blood cells
Breast cancer
Breast Neoplasms - diagnostic imaging
Carbon
Carbon - chemistry
Diagnosis
Female
Fluorescence
Fluorescent Dyes - chemistry
Humans
Immunity, Cellular - immunology
Leukocytes, Mononuclear - immunology
Leukocytes, Mononuclear - pathology
Optical Imaging
Polymers
Polymers - chemistry
Quantum Dots - chemistry
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Summary:We constructed a carbon-based polymer dot (CPD) sensor to detect breast cancer based on the differences of peripheral blood cells, providing a new minimally invasive method for cancer diagnosis. This simple and extensible system exhibits clinically relevant accuracy in terms of cancer identification, making it an attractive strategy for diagnosis and prognosis. A carbon-based polymer dot (CPD) sensor can quickly and accurately detect cancer mice using peripheral blood immunocytes.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc10016d