A dual-ratiometric fluorescent probe for individual and continuous detection of HS and HClO in living cells

HClO and H 2 S are crucial for maintaining the homeostasis in cells and play vital roles in many physiological and pathological processes. Herein, we present a fluorescent probe that can respectively and simultaneously detect H 2 S and HClO in a dual-ratiometric manner with good linearity. Utilizing...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (19), p.2849-2852
Main Authors: Yue, Xiuxiu, Wang, Jingpei, Han, Jinliang, Wang, Benhua, Song, Xiangzhi
Format: Article
Language:English
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Summary:HClO and H 2 S are crucial for maintaining the homeostasis in cells and play vital roles in many physiological and pathological processes. Herein, we present a fluorescent probe that can respectively and simultaneously detect H 2 S and HClO in a dual-ratiometric manner with good linearity. Utilizing this probe, the imaging of intracellular H 2 S or/and HClO in living cells in a ratiometric manner was achieved. A dual-ratiometric fluorescent probe, Han-HClO-H 2 S , was developed for the individual and continuous detection of H 2 S and HClO with high sensitivity and good selectivity, and had been applied to detect intracellular H 2 S and/or HClO in living cells.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc10028h