A ratiometric and colorimetric probe for detecting Hg based on naphthalimide-rhodamine and its staining function in cell imaging

In this work, a rhodamine derivative was developed as a colorimetric and ratiometric fluorescent probe for Hg 2+ . It exhibited a highly sensitive fluorescence response toward Hg 2+ . Importantly, studies revealed that the probe could be used for ratiometric detection of Hg 2+ , with a low detection...

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Bibliographic Details
Published in:RSC advances 2019-04, Vol.9 (21), p.11664-11669
Main Authors: Wang, Yuesong, Ding, Haichang, Wang, Shuai, Fan, Congbin, Tu, Yayi, Liu, Gang, Pu, Shouzhi
Format: Article
Language:English
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Summary:In this work, a rhodamine derivative was developed as a colorimetric and ratiometric fluorescent probe for Hg 2+ . It exhibited a highly sensitive fluorescence response toward Hg 2+ . Importantly, studies revealed that the probe could be used for ratiometric detection of Hg 2+ , with a low detection limit of 0.679 μM. The mechanism of Hg 2+ detection using compound 1 was confirmed by ESI-MS, 1 H NMR, and HPLC. Upon the addition of Hg 2+ , the rhodamine receptor was induced to be in the ring-opening form via an Hg 2+ -promoted hydrolysis of rhodamine hydrazide to rhodamine acid. In addition to Hg 2+ detection, the naphthalimide-rhodamine compound was proven to be effective in cell imaging. A new probe based on naphthalimide-rhodamine was applied in recognition of Hg 2+ by a FRET mechanism.
ISSN:2046-2069
DOI:10.1039/c9ra01459d