Direct synthesis of 2-substituted benzonitriles alkylcyanation of arynes with ,-disubstituted aminomalononitriles

An efficient alkylcyanation of in situ generated arynes by N , N -disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles. An efficient alkylcyanation of in situ generated arynes by N , N -disubstituted aminomalononitriles is described, enabling t...

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Published in:Chemical communications (Cambridge, England) England), 2020-07, Vol.56 (55), p.7641-7644
Main Authors: Bao, Wen, Gao, Zhu-Peng, Jin, Da-Ping, Xue, Cao-Gen, Liang, Huan, Lei, Ling-Sheng, Xu, Xue-Tao, Zhang, Kun, Wang, Shao-Hua
Format: Article
Language:English
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Summary:An efficient alkylcyanation of in situ generated arynes by N , N -disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles. An efficient alkylcyanation of in situ generated arynes by N , N -disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc01591a