Arylation of (hetero)arylamines using aryl sulfamates and carbamates C-O bond activation enabled by a reusable and durable nickel(0) catalyst

• Published in: New journal of chemistry 2020-08, Vol.44 (31), p.13266-13278
• Main Authors: Dindarloo Inaloo, Iman, Majnooni, Sahar, Eslahi, Hassan, Esmaeilpour, Mohsen
• Format: Article
• Language: English
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/d0nj01610a

An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst. This new stable catalyst was prepared on Fe 3 O 4 @SiO 2 modified by EDTA and investigated by FT-IR, EDX, TEM, XRD, DLS, FE-SEM, XPS, NMR, TGA, VSM, ICP and elemental analysis techniques. The reaction proceeded via carbon-oxygen bond cleavage of (hetero)aryl carbamates and sulfamates under simple and mild conditions without the use of any external ligands. This method demonstrated functional group tolerance in the N -arylation of various nitrogen-containing compounds as well as aliphatic amines, anilines, pyrroles, pyrazoles, imidazoles, indoles, and indazoles with good to excellent yields. Furthermore, the catalyst could be easily recovered by using an external magnetic field and directly reused at least six times without notable reduction in its activity. An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst.