Amide-imine conjugate involving gallic acid and naphthalene for nano-molar detection, enrichment and cancer cell imaging of La: studies on the catalytic activity of the La complex

• Published in: New journal of chemistry 2020-08, Vol.44 (31), p.1351-1356
• Main Authors: Shaikh, Ahad, Ghosh, Milan, Mukherjee, Pallabi, Ghosh, Avijit, Molla, Rostam Ali, Ta, Sabyasachi, Das, Debasis
• Format: Article
• Language: English
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/d0nj02415e

A single crystal X-ray structurally characterized amide-imine conjugate ( GAN ) derived from gallic acid and naphthalene selectively recognizes La 3+ ions via TURN ON fluorescence through ESIPT and CHEF mechanisms. GAN can detect as low as 23.93 × 10 −9 M La 3+ ions and image intracellular La 3+ ions in live HeLa and SiHa cells under a fluorescence microscope in a time- and concentration dependent manner. The corresponding [ La( iii )-GAN ] complex is established as an efficient catalyst for the synthesis of benzimidazole derivatives from o -phenylenediamine and substituted benzaldehydes. Moreover, GAN is very useful for enrichment of La 3+ in ethyl acetate medium. A single crystal X-ray structurally characterized amide-imine conjugate ( GAN ) derived from gallic acid and naphthalene selectively recognizes La 3+ ion via TURN ON fluorescence through ESIPT and CHEF mechanisms.