Loading…
BiSI nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows
Near-infrared (NIR) light-induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in photothermal therapy systems, a variety of photothermal agents have been developed. However, the explora...
Saved in:
Published in: | Nanoscale 2021-03, Vol.13 (1), p.5369-5382 |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article |
Language: | |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | |
container_end_page | 5382 |
container_issue | 1 |
container_start_page | 5369 |
container_title | Nanoscale |
container_volume | 13 |
creator | Xiong, Jinsong Bian, Qinghuan Lei, Shuijin Deng, Yatian Zhao, Kehan Sun, Shunqiang Fu, Qi Xiao, Yanhe Cheng, Baochang |
description | Near-infrared (NIR) light-induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in photothermal therapy systems, a variety of photothermal agents have been developed. However, the exploration of novel photothermal therapy nanoplatforms with high NIR absorption remains a significant challenge, especially those working in both NIR-I and NIR-II windows. In this work, Bi
19
S
27
I
3
nanorods with remarkably high absorption covering the whole visible light to the entire NIR-I and NIR-II regions have been successfully prepared through a facile solvothermal approach. The as-synthesized Bi
19
S
27
I
3
nanorods have a high photothermal conversion efficiency of 42.7% at 808 nm (NIR-I) and 41.5% at 1064 nm (NIR-II), making them a promising candidate for photothermal therapy.
In vitro
cell viability assay reveals that the Bi
19
S
27
I
3
sample has good biocompatibility and exhibits significant cell-killing effect under NIR irradiation.
In vivo
anti-tumor experiments demonstrate that the tumor growth can be effectively inhibited by fatal hyperthermia ablation mediated by Bi
19
S
27
I
3
nanorods under the irradiation of an 808 nm or 1064 nm laser. Therefore, this study should be primarily beneficial for the development of new materials for NIR photothermal therapy applications.
For the first time, Bi
19
S
27
I
3
nanorods are utilized as a promising nanoplatform for photothermal therapy in NIR-I and NIR-II windows. |
doi_str_mv | 10.1039/d0nr09137e |
format | article |
fullrecord | <record><control><sourceid>rsc</sourceid><recordid>TN_cdi_rsc_primary_d0nr09137e</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>d0nr09137e</sourcerecordid><originalsourceid>FETCH-rsc_primary_d0nr09137e3</originalsourceid><addsrcrecordid>eNqFj0FrwkAQRpdSoan24l2YP5B2k5VIPFpa2rO9hzG7qSNxJswGQv69EcQee3oPvnf5jFlm9jWzrnzzltWWmduEB5Pkdm1T5zb5492L9ZN5jvFkbVG6wiWm29H-GxhZVHzcAgKHAWpkTx77AI0odEfppT8GPWMLV2I3AvFVoSGNPUw5xFDLhANJK79UTykH1JS4UdTgYSD2MsSFmTXYxvBy49ysPj9-3r9SjXXVKZ1Rx-rvhvtvvwB_NEze</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>BiSI nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows</title><source>Royal Society of Chemistry</source><creator>Xiong, Jinsong ; Bian, Qinghuan ; Lei, Shuijin ; Deng, Yatian ; Zhao, Kehan ; Sun, Shunqiang ; Fu, Qi ; Xiao, Yanhe ; Cheng, Baochang</creator><creatorcontrib>Xiong, Jinsong ; Bian, Qinghuan ; Lei, Shuijin ; Deng, Yatian ; Zhao, Kehan ; Sun, Shunqiang ; Fu, Qi ; Xiao, Yanhe ; Cheng, Baochang</creatorcontrib><description>Near-infrared (NIR) light-induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in photothermal therapy systems, a variety of photothermal agents have been developed. However, the exploration of novel photothermal therapy nanoplatforms with high NIR absorption remains a significant challenge, especially those working in both NIR-I and NIR-II windows. In this work, Bi
19
S
27
I
3
nanorods with remarkably high absorption covering the whole visible light to the entire NIR-I and NIR-II regions have been successfully prepared through a facile solvothermal approach. The as-synthesized Bi
19
S
27
I
3
nanorods have a high photothermal conversion efficiency of 42.7% at 808 nm (NIR-I) and 41.5% at 1064 nm (NIR-II), making them a promising candidate for photothermal therapy.
In vitro
cell viability assay reveals that the Bi
19
S
27
I
3
sample has good biocompatibility and exhibits significant cell-killing effect under NIR irradiation.
In vivo
anti-tumor experiments demonstrate that the tumor growth can be effectively inhibited by fatal hyperthermia ablation mediated by Bi
19
S
27
I
3
nanorods under the irradiation of an 808 nm or 1064 nm laser. Therefore, this study should be primarily beneficial for the development of new materials for NIR photothermal therapy applications.
For the first time, Bi
19
S
27
I
3
nanorods are utilized as a promising nanoplatform for photothermal therapy in NIR-I and NIR-II windows.</description><identifier>ISSN: 2040-3364</identifier><identifier>EISSN: 2040-3372</identifier><identifier>DOI: 10.1039/d0nr09137e</identifier><ispartof>Nanoscale, 2021-03, Vol.13 (1), p.5369-5382</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Xiong, Jinsong</creatorcontrib><creatorcontrib>Bian, Qinghuan</creatorcontrib><creatorcontrib>Lei, Shuijin</creatorcontrib><creatorcontrib>Deng, Yatian</creatorcontrib><creatorcontrib>Zhao, Kehan</creatorcontrib><creatorcontrib>Sun, Shunqiang</creatorcontrib><creatorcontrib>Fu, Qi</creatorcontrib><creatorcontrib>Xiao, Yanhe</creatorcontrib><creatorcontrib>Cheng, Baochang</creatorcontrib><title>BiSI nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows</title><title>Nanoscale</title><description>Near-infrared (NIR) light-induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in photothermal therapy systems, a variety of photothermal agents have been developed. However, the exploration of novel photothermal therapy nanoplatforms with high NIR absorption remains a significant challenge, especially those working in both NIR-I and NIR-II windows. In this work, Bi
19
S
27
I
3
nanorods with remarkably high absorption covering the whole visible light to the entire NIR-I and NIR-II regions have been successfully prepared through a facile solvothermal approach. The as-synthesized Bi
19
S
27
I
3
nanorods have a high photothermal conversion efficiency of 42.7% at 808 nm (NIR-I) and 41.5% at 1064 nm (NIR-II), making them a promising candidate for photothermal therapy.
In vitro
cell viability assay reveals that the Bi
19
S
27
I
3
sample has good biocompatibility and exhibits significant cell-killing effect under NIR irradiation.
In vivo
anti-tumor experiments demonstrate that the tumor growth can be effectively inhibited by fatal hyperthermia ablation mediated by Bi
19
S
27
I
3
nanorods under the irradiation of an 808 nm or 1064 nm laser. Therefore, this study should be primarily beneficial for the development of new materials for NIR photothermal therapy applications.
For the first time, Bi
19
S
27
I
3
nanorods are utilized as a promising nanoplatform for photothermal therapy in NIR-I and NIR-II windows.</description><issn>2040-3364</issn><issn>2040-3372</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFj0FrwkAQRpdSoan24l2YP5B2k5VIPFpa2rO9hzG7qSNxJswGQv69EcQee3oPvnf5jFlm9jWzrnzzltWWmduEB5Pkdm1T5zb5492L9ZN5jvFkbVG6wiWm29H-GxhZVHzcAgKHAWpkTx77AI0odEfppT8GPWMLV2I3AvFVoSGNPUw5xFDLhANJK79UTykH1JS4UdTgYSD2MsSFmTXYxvBy49ysPj9-3r9SjXXVKZ1Rx-rvhvtvvwB_NEze</recordid><startdate>20210318</startdate><enddate>20210318</enddate><creator>Xiong, Jinsong</creator><creator>Bian, Qinghuan</creator><creator>Lei, Shuijin</creator><creator>Deng, Yatian</creator><creator>Zhao, Kehan</creator><creator>Sun, Shunqiang</creator><creator>Fu, Qi</creator><creator>Xiao, Yanhe</creator><creator>Cheng, Baochang</creator><scope/></search><sort><creationdate>20210318</creationdate><title>BiSI nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows</title><author>Xiong, Jinsong ; Bian, Qinghuan ; Lei, Shuijin ; Deng, Yatian ; Zhao, Kehan ; Sun, Shunqiang ; Fu, Qi ; Xiao, Yanhe ; Cheng, Baochang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_d0nr09137e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><creationdate>2021</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xiong, Jinsong</creatorcontrib><creatorcontrib>Bian, Qinghuan</creatorcontrib><creatorcontrib>Lei, Shuijin</creatorcontrib><creatorcontrib>Deng, Yatian</creatorcontrib><creatorcontrib>Zhao, Kehan</creatorcontrib><creatorcontrib>Sun, Shunqiang</creatorcontrib><creatorcontrib>Fu, Qi</creatorcontrib><creatorcontrib>Xiao, Yanhe</creatorcontrib><creatorcontrib>Cheng, Baochang</creatorcontrib><jtitle>Nanoscale</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xiong, Jinsong</au><au>Bian, Qinghuan</au><au>Lei, Shuijin</au><au>Deng, Yatian</au><au>Zhao, Kehan</au><au>Sun, Shunqiang</au><au>Fu, Qi</au><au>Xiao, Yanhe</au><au>Cheng, Baochang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>BiSI nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows</atitle><jtitle>Nanoscale</jtitle><date>2021-03-18</date><risdate>2021</risdate><volume>13</volume><issue>1</issue><spage>5369</spage><epage>5382</epage><pages>5369-5382</pages><issn>2040-3364</issn><eissn>2040-3372</eissn><abstract>Near-infrared (NIR) light-induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in photothermal therapy systems, a variety of photothermal agents have been developed. However, the exploration of novel photothermal therapy nanoplatforms with high NIR absorption remains a significant challenge, especially those working in both NIR-I and NIR-II windows. In this work, Bi
19
S
27
I
3
nanorods with remarkably high absorption covering the whole visible light to the entire NIR-I and NIR-II regions have been successfully prepared through a facile solvothermal approach. The as-synthesized Bi
19
S
27
I
3
nanorods have a high photothermal conversion efficiency of 42.7% at 808 nm (NIR-I) and 41.5% at 1064 nm (NIR-II), making them a promising candidate for photothermal therapy.
In vitro
cell viability assay reveals that the Bi
19
S
27
I
3
sample has good biocompatibility and exhibits significant cell-killing effect under NIR irradiation.
In vivo
anti-tumor experiments demonstrate that the tumor growth can be effectively inhibited by fatal hyperthermia ablation mediated by Bi
19
S
27
I
3
nanorods under the irradiation of an 808 nm or 1064 nm laser. Therefore, this study should be primarily beneficial for the development of new materials for NIR photothermal therapy applications.
For the first time, Bi
19
S
27
I
3
nanorods are utilized as a promising nanoplatform for photothermal therapy in NIR-I and NIR-II windows.</abstract><doi>10.1039/d0nr09137e</doi><tpages>14</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2040-3364 |
ispartof | Nanoscale, 2021-03, Vol.13 (1), p.5369-5382 |
issn | 2040-3364 2040-3372 |
language | |
recordid | cdi_rsc_primary_d0nr09137e |
source | Royal Society of Chemistry |
title | BiSI nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T11%3A36%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-rsc&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=BiSI%20nanorods:%20a%20new%20candidate%20for%20photothermal%20therapy%20in%20the%20first%20and%20second%20biological%20near-infrared%20windows&rft.jtitle=Nanoscale&rft.au=Xiong,%20Jinsong&rft.date=2021-03-18&rft.volume=13&rft.issue=1&rft.spage=5369&rft.epage=5382&rft.pages=5369-5382&rft.issn=2040-3364&rft.eissn=2040-3372&rft_id=info:doi/10.1039/d0nr09137e&rft_dat=%3Crsc%3Ed0nr09137e%3C/rsc%3E%3Cgrp_id%3Ecdi_FETCH-rsc_primary_d0nr09137e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |