Loading…
A Rh()/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives a formal [3 + 2]-cycloaddition
A novel dearomatization/rearomatization/cyclization oxonium ylide trapping process is well developed via a dirhodium( ii ) acetate and phosphoric acid cooperatively catalyzed multi-component reaction of diazo-ketones with alcohols and azonaphthalenes. This protocol provides an efficient route to syn...
Saved in:
| Published in: | Organic & biomolecular chemistry 2020-12, Vol.18 (48), p.985-989 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | |
| container_end_page | 989 |
| container_issue | 48 |
| container_start_page | 985 |
| container_title | Organic & biomolecular chemistry |
| container_volume | 18 |
| creator | Yin, Xinru Xu, Aimin Hu, Jidi Bao, Ming Hu, Wenhao Qian, Yu |
| description | A novel dearomatization/rearomatization/cyclization oxonium ylide trapping process is well developed
via
a dirhodium(
ii
) acetate and phosphoric acid cooperatively catalyzed multi-component reaction of diazo-ketones with alcohols and azonaphthalenes. This protocol provides an efficient route to synthesize
N
-substituted 1-amino-indole derivatives in good yield under mild reaction conditions.
Rh(
ii
)/Phosphoric Acid co-catalyzed muti-component annulation was well established as a new efficient route to construct 1-amino-indole derivatives
via
dearomatization/rearomatization/cyclization process with
in situ
formed oxonium ylide. |
| doi_str_mv | 10.1039/d0ob02189j |
| format | article |
| fullrecord | <record><control><sourceid>rsc</sourceid><recordid>TN_cdi_rsc_primary_d0ob02189j</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>d0ob02189j</sourcerecordid><originalsourceid>FETCH-rsc_primary_d0ob02189j3</originalsourceid><addsrcrecordid>eNqFkE9LxDAQxYMouP65eBfmqEjctF2t9SaL4lm8iSxjMiVZ00xJwkr3M_khjSB69DDMwO_Ne_CEOKnUZaWabm4Uv6m6uunWO2JWLdpWqqum2_29a7UvDlJaK1V17fViJj7v4Mmenc9Hy6lMdBpQOwOapcaMftqSgWwjkdQ8jBwoZIiEOjsOwD0Yh1uW75QLSvDhsgX0mi37BBgMFBpwtNmip6K4LfaaUoLM4IJhT2Aoug1mtyn_CD3HAT28NHAB9avUk_aMxrjvvCOx16NPdPyzD8Xpw_3z8lHGpFdjdAPGafVXQfMf_wJkzWJ6</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A Rh()/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives a formal [3 + 2]-cycloaddition</title><source>Royal Society of Chemistry</source><creator>Yin, Xinru ; Xu, Aimin ; Hu, Jidi ; Bao, Ming ; Hu, Wenhao ; Qian, Yu</creator><creatorcontrib>Yin, Xinru ; Xu, Aimin ; Hu, Jidi ; Bao, Ming ; Hu, Wenhao ; Qian, Yu</creatorcontrib><description>A novel dearomatization/rearomatization/cyclization oxonium ylide trapping process is well developed
via
a dirhodium(
ii
) acetate and phosphoric acid cooperatively catalyzed multi-component reaction of diazo-ketones with alcohols and azonaphthalenes. This protocol provides an efficient route to synthesize
N
-substituted 1-amino-indole derivatives in good yield under mild reaction conditions.
Rh(
ii
)/Phosphoric Acid co-catalyzed muti-component annulation was well established as a new efficient route to construct 1-amino-indole derivatives
via
dearomatization/rearomatization/cyclization process with
in situ
formed oxonium ylide.</description><identifier>ISSN: 1477-0520</identifier><identifier>EISSN: 1477-0539</identifier><identifier>DOI: 10.1039/d0ob02189j</identifier><ispartof>Organic & biomolecular chemistry, 2020-12, Vol.18 (48), p.985-989</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Yin, Xinru</creatorcontrib><creatorcontrib>Xu, Aimin</creatorcontrib><creatorcontrib>Hu, Jidi</creatorcontrib><creatorcontrib>Bao, Ming</creatorcontrib><creatorcontrib>Hu, Wenhao</creatorcontrib><creatorcontrib>Qian, Yu</creatorcontrib><title>A Rh()/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives a formal [3 + 2]-cycloaddition</title><title>Organic & biomolecular chemistry</title><description>A novel dearomatization/rearomatization/cyclization oxonium ylide trapping process is well developed
via
a dirhodium(
ii
) acetate and phosphoric acid cooperatively catalyzed multi-component reaction of diazo-ketones with alcohols and azonaphthalenes. This protocol provides an efficient route to synthesize
N
-substituted 1-amino-indole derivatives in good yield under mild reaction conditions.
Rh(
ii
)/Phosphoric Acid co-catalyzed muti-component annulation was well established as a new efficient route to construct 1-amino-indole derivatives
via
dearomatization/rearomatization/cyclization process with
in situ
formed oxonium ylide.</description><issn>1477-0520</issn><issn>1477-0539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFkE9LxDAQxYMouP65eBfmqEjctF2t9SaL4lm8iSxjMiVZ00xJwkr3M_khjSB69DDMwO_Ne_CEOKnUZaWabm4Uv6m6uunWO2JWLdpWqqum2_29a7UvDlJaK1V17fViJj7v4Mmenc9Hy6lMdBpQOwOapcaMftqSgWwjkdQ8jBwoZIiEOjsOwD0Yh1uW75QLSvDhsgX0mi37BBgMFBpwtNmip6K4LfaaUoLM4IJhT2Aoug1mtyn_CD3HAT28NHAB9avUk_aMxrjvvCOx16NPdPyzD8Xpw_3z8lHGpFdjdAPGafVXQfMf_wJkzWJ6</recordid><startdate>20201223</startdate><enddate>20201223</enddate><creator>Yin, Xinru</creator><creator>Xu, Aimin</creator><creator>Hu, Jidi</creator><creator>Bao, Ming</creator><creator>Hu, Wenhao</creator><creator>Qian, Yu</creator><scope/></search><sort><creationdate>20201223</creationdate><title>A Rh()/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives a formal [3 + 2]-cycloaddition</title><author>Yin, Xinru ; Xu, Aimin ; Hu, Jidi ; Bao, Ming ; Hu, Wenhao ; Qian, Yu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_d0ob02189j3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><creationdate>2020</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yin, Xinru</creatorcontrib><creatorcontrib>Xu, Aimin</creatorcontrib><creatorcontrib>Hu, Jidi</creatorcontrib><creatorcontrib>Bao, Ming</creatorcontrib><creatorcontrib>Hu, Wenhao</creatorcontrib><creatorcontrib>Qian, Yu</creatorcontrib><jtitle>Organic & biomolecular chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yin, Xinru</au><au>Xu, Aimin</au><au>Hu, Jidi</au><au>Bao, Ming</au><au>Hu, Wenhao</au><au>Qian, Yu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Rh()/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives a formal [3 + 2]-cycloaddition</atitle><jtitle>Organic & biomolecular chemistry</jtitle><date>2020-12-23</date><risdate>2020</risdate><volume>18</volume><issue>48</issue><spage>985</spage><epage>989</epage><pages>985-989</pages><issn>1477-0520</issn><eissn>1477-0539</eissn><abstract>A novel dearomatization/rearomatization/cyclization oxonium ylide trapping process is well developed
via
a dirhodium(
ii
) acetate and phosphoric acid cooperatively catalyzed multi-component reaction of diazo-ketones with alcohols and azonaphthalenes. This protocol provides an efficient route to synthesize
N
-substituted 1-amino-indole derivatives in good yield under mild reaction conditions.
Rh(
ii
)/Phosphoric Acid co-catalyzed muti-component annulation was well established as a new efficient route to construct 1-amino-indole derivatives
via
dearomatization/rearomatization/cyclization process with
in situ
formed oxonium ylide.</abstract><doi>10.1039/d0ob02189j</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1477-0520 |
| ispartof | Organic & biomolecular chemistry, 2020-12, Vol.18 (48), p.985-989 |
| issn | 1477-0520 1477-0539 |
| language | |
| recordid | cdi_rsc_primary_d0ob02189j |
| source | Royal Society of Chemistry |
| title | A Rh()/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives a formal [3 + 2]-cycloaddition |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T16%3A11%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-rsc&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Rh()/phosphoric%20acid%20co-catalyzed%20three-component%20reaction%20of%20diazo-ketones%20with%20alcohols%20and%20azonaphthalenes:%20access%20to%20indole%20derivatives%20a%20formal%20%5B3%20+%202%5D-cycloaddition&rft.jtitle=Organic%20&%20biomolecular%20chemistry&rft.au=Yin,%20Xinru&rft.date=2020-12-23&rft.volume=18&rft.issue=48&rft.spage=985&rft.epage=989&rft.pages=985-989&rft.issn=1477-0520&rft.eissn=1477-0539&rft_id=info:doi/10.1039/d0ob02189j&rft_dat=%3Crsc%3Ed0ob02189j%3C/rsc%3E%3Cgrp_id%3Ecdi_FETCH-rsc_primary_d0ob02189j3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |