Metal ion and light sequentially induced sol-gel-sol transition of a responsive peptide-hydrogel

We developed a new responsive peptide hydrogel FmocFFpS C (oNB)-PEG, which could achieve gel formation induced by calcium ions and sequential dissolution stimulated by light. It provides a potential delivery system for the efficient encapsulation of drugs and their controlled release in a spatial an...

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Bibliographic Details
Published in:Soft matter 2020-08, Vol.16 (33), p.7652-7658
Main Authors: Zhang, Yun-Lai, Chang, Rong, Duan, Hua-Zhen, Chen, Yong-Xiang
Format: Article
Language:English
Subjects:
Calcium
Calcium ions
Controlled release
Drug delivery
Drug delivery systems
Hydrogels
Metal ions
Peptides
Sol-gel processes
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Summary:We developed a new responsive peptide hydrogel FmocFFpS C (oNB)-PEG, which could achieve gel formation induced by calcium ions and sequential dissolution stimulated by light. It provides a potential delivery system for the efficient encapsulation of drugs and their controlled release in a spatial and temporal way. We developed a new responsive peptide hydrogel that could achieve a sol-gel-sol transition sequentially induced by calcium ions and light.
ISSN:1744-683X
1744-6848
DOI:10.1039/d0sm00442a