Co-biomembrane-coated FeO/MnO multifunctional nanoparticles for targeted delivery and enhanced chemodynamic/photothermal/chemo therapy

Here, the co-membrane system of MCF-7 breast cancer cell membrane (MM) and Escherichia coli membrane (EM)-coated Fe 3 O 4 /MnO 2 multifunctional composite nanoparticles loaded with DOX (Fe 3 O 4 /MnO 2 /MM/EM/D) was used for targeted drug delivery and biological imaging. Fe 3 O 4 /MnO 2 biomimetic n...

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Published in:Chemical communications (Cambridge, England) England), 2021-06, Vol.57 (47), p.5754-5757
Main Authors: Guo, Yingshu, Zheng, Xiaofei, Gai, Tingting, Wei, Zhiyong, Zhang, Shusheng
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Summary:Here, the co-membrane system of MCF-7 breast cancer cell membrane (MM) and Escherichia coli membrane (EM)-coated Fe 3 O 4 /MnO 2 multifunctional composite nanoparticles loaded with DOX (Fe 3 O 4 /MnO 2 /MM/EM/D) was used for targeted drug delivery and biological imaging. Fe 3 O 4 /MnO 2 biomimetic nanoplatform has good Fenton catalytic activity and photothermal conversion efficiency, combined with good targeting ability, which can be used to improve the therapeutic efficiency.
ISSN:1359-7345
1364-548X
DOI:10.1039/d1cc01375k