B(CF)-Catalyzed transfer hydrogenation of esters and organic carbonates towards alcohols with ammonia borane

Herein, we report an efficient metal-free system for the transfer hydrogenation of esters and carbonates by-passing the otherwise ubiquitous formation of transesterification side-products. The Lewis acid B(C 6 F 5 ) 3 is used as catalyst and ammonia borane as hydrogen donor. This methodology shows b...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2022-05, Vol.58 (41), p.6144-6147
Main Authors: Guo, Xuewen, Unglaube, Felix, Kragl, Udo, Mejía, Esteban
Format: Article
Language:English
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Summary:Herein, we report an efficient metal-free system for the transfer hydrogenation of esters and carbonates by-passing the otherwise ubiquitous formation of transesterification side-products. The Lewis acid B(C 6 F 5 ) 3 is used as catalyst and ammonia borane as hydrogen donor. This methodology shows broad substrate scope and functional group tolerance in excellent yields at very mild conditions. Herein, we report an efficient metal-free system for the transfer hydrogenation of esters and carbonates with ammonia borane as hydrogen donor, by-passing the otherwise ubiquitous formation of transesterification side-products.
ISSN:1359-7345
1364-548X
DOI:10.1039/d2cc01442d