A BOPHY based fluorescent probe for Hg NTe chelation

A BOPHY-based organotellurium-containing probe was synthesized and characterized via single crystal XRD for the selective and sensitive detection of Hg 2+ over other metal ions. The probe detects Hg 2+ in less than 1 s with a 2.5-fold enhancement in fluorescent intensity. Due to the chalcogenophilic...

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Published in:Dalton transactions : an international journal of inorganic chemistry 2022-07, Vol.51 (26), p.169-176
Main Authors: Malankar, Gauri S, Shelar, Divyesh S, Patra, Malay, Butcher, Ray J, Manjare, Sudesh T
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Summary:A BOPHY-based organotellurium-containing probe was synthesized and characterized via single crystal XRD for the selective and sensitive detection of Hg 2+ over other metal ions. The probe detects Hg 2+ in less than 1 s with a 2.5-fold enhancement in fluorescent intensity. Due to the chalcogenophilicity of mercury, Hg 2+ was facilely trapped in the NTe 2 chelating cavity of the probe. The probe can detect Hg 2+ in the nanomolar range (62 nM) and it showed reversibility with S 2− ions. The sensitivity of the probe for the detection of Hg 2+ was confirmed in living HeLa cells. The first tellurium derivative of BOPHY is reported. The probe could detect Hg 2+ inside HeLa cells with an instantaneous fluorescence turn-on response in the nanomolar range.
ISSN:1477-9226
1477-9234
DOI:10.1039/d2dt01086k