Loading…
New antimicrobial materials with cerium ions in the composition of salts, solutions, and composite systems based on Ce(NO) 6HO
The results of detailed characterization of new antimicrobial materials in the form of Ce(NO 3 ) 3 × 6H 2 O salt with the proposed crystal-chemical composition of [Ce 3+ (H 2 O) 4 (NO 3 ) 3 ] × 2H 2 O and its aqueous solution by X-ray diffraction (XRD), differential scanning calorimetry (DSC), X-ray...
Saved in:
| Published in: | New journal of chemistry 2022-10, Vol.46 (4), p.19271-19282 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The results of detailed characterization of new antimicrobial materials in the form of Ce(NO
3
)
3
× 6H
2
O salt with the proposed crystal-chemical composition of [Ce
3+
(H
2
O)
4
(NO
3
)
3
] × 2H
2
O and its aqueous solution by X-ray diffraction (XRD), differential scanning calorimetry (DSC), X-ray photoelectron spectroscopy (XPS), X-ray absorption spectroscopy (XAS) are presented. The stages of [Ce
3+
(H
2
O)
4
(NO
3
)
3
] × 2H
2
O thermal decomposition with the formation of [Ce
3+
(H
2
O)
4
(NO
3
)
3
] (300 C) are shown. It was found that Ce
3+
ions in the composition of [Ce(H
2
O)
4
(NO
3
)
3
] × 2H
2
O salt and in its aqueous solution retain their formal charge (FC Ce = 3) and coordination number (CNCe = 10, where 6O from three NO
3
−
groups and 4O from four 4H
2
O molecules) with the reorientation of nitro groups in Ce
3+
far environment in an aqueous salt solution. It was established that [Ce
3+
(H
2
O)
4
(NO
3
)
3
] 2H
2
O, [Ce
3+
(H
2
O)
4
(NO
3
)
3
] and Ce
3+
ONO
3
salts inhibit the growth of
Staphylococcus aureus
,
Escherichia coli
and
Pseudomonas aeruginosa
bacteria in the absence of radiation with a growth zone inhibition diameter
D
> 37 mm with
D
max
= 45 mm on the multiphase sample ([Ce
3+
(H
2
O)
4
(NO
3
)
3
], Ce
3+
ONO
3
, Ce
4+
O
2
), which is higher than that on penicillin (
D
= 1218 mm). It is shown that an increase in the [Ce
3+
(H
2
O)
4
(NO
3
)
3
] 2H
2
O salt concentration in an aqueous solution has a positive effect on antimicrobial activity. It is not excluded that the absence of interaction of Ce
3+
ions in the salt solution with Langmuir phospholipid monolayers of phosphatidylethanolamine (DPPE) and phosphatidylglycerin (DPPG) is associated with the damage to the protein component of the bacterial membrane and not with the phospholipid one and/or with the "penetration" of Ce
3+
ions into the cell and violation of its water-ionic balance. It is shown that the H-Beta - Ce
3+
(NO
3
)
3
6H
2
O system fabrication with biocompatible H-Beta zeolite contributes to the preservation of antimicrobial activity in the dark (
Pseudomonas aeruginosa
) with a decrease in the amount of the active component.
The antimicrobial property against different bacteria with cerium oxide formation mainly depends on the content of Ce
3+
ions. |
|---|---|
| ISSN: | 1144-0546 1369-9261 |
| DOI: | 10.1039/d2nj03691f |