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Developing an electrochemical sensor for the measurements of dopamine

Measurements inside the human body are complicated. Here, we provide a short introduction of the main requirements for the successful in vivo determination of dopamine concentrations, together with a discussion of how the type of the measurements, short-term vs. long-term and dynamic vs. basal measu...

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Bibliographic Details
Published in:Sensors & diagnostics 2023-05, Vol.2 (3), p.559-581
Main Authors: Delmo, Naela, Mostafiz, Bahar, Ross, Ashley E, Suni, Johanna, Peltola, Emilia
Format: Article
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Summary:Measurements inside the human body are complicated. Here, we provide a short introduction of the main requirements for the successful in vivo determination of dopamine concentrations, together with a discussion of how the type of the measurements, short-term vs. long-term and dynamic vs. basal measurements, affects what is expected from the sensor material. Next, we provide a step-by-step guide for characterising electrode performance and performing in vivo measurements with practical tips. Finally, we discuss the typical approaches for overcoming the challenges set by the environment. Measurements inside the human body are complicated.
ISSN:2635-0998
DOI:10.1039/d2sd00230b