Catalytic prenylation of natural polyphenols

Prenylated polyphenols occur naturally and exhibit biological activity superior to the ubiquitous parent polyphenols. However, their low abundance limits the wider application of these derivatives. In this work, we present an expedient, single-step catalytic protocol for introducing terpene fragment...

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Bibliographic Details
Published in:New journal of chemistry 2023-11, Vol.47 (44), p.2358-2362
Main Authors: Du, Yi, Korchi, Iman, Rubtsov, Aleksandr E, Malkov, Andrei V
Format: Article
Language:English
Subjects:
Aromatic compounds
Biological activity
Flavonoids
Polyphenols
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Summary:Prenylated polyphenols occur naturally and exhibit biological activity superior to the ubiquitous parent polyphenols. However, their low abundance limits the wider application of these derivatives. In this work, we present an expedient, single-step catalytic protocol for introducing terpene fragments into the aromatic rings of the widely available natural stilbenoids and flavonoids to upgrade their therapeutic potential. Prenylated polyphenols occur naturally and exhibit biological activity superior to the ubiquitous parent polyphenols.
ISSN:1144-0546
1369-9261
DOI:10.1039/d3nj04371a