Are neuropsychological changes relevant in subclinical hypothyroidism?

Neuropsychological changes are still controversial in patients with subclinical hypothyroidism (SH). The objective of this study is to assess these changes. Cross-sectional study comparing the results of the neurocognitive evaluation of 65 SH patients and 31 individuals without thyroid disease. Subc...

Full description

Saved in:
Bibliographic Details
Published in:Arquivos brasileiros de endocrinologia e metabologia 2007-06, Vol.51 (4), p.606-611
Main Authors: Almeida, Cloyra, Vaisman, Mario, Costa, Antonio José Leal, Reis, Fabiola A A, Reuters, Vaneska, Teixeira, Patricia, Ferreira, Marcia, Teixeira, Letícia B B de M, Araújo, Glória R B de, Brasil, Marco Antonio
Format: Article
Language:English
Subjects:
Adult
Cognition
Cross-Sectional Studies
ENDOCRINOLOGY & METABOLISM
Female
Humans
Hypothyroidism - blood
Hypothyroidism - diagnosis
Hypothyroidism - psychology
Male
Mental Disorders - diagnosis
Middle Aged
Neuropsychological Tests
Thyroid Gland - physiopathology
Thyrotropin - blood
Thyroxine - blood
Wechsler Scales
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Neuropsychological changes are still controversial in patients with subclinical hypothyroidism (SH). The objective of this study is to assess these changes. Cross-sectional study comparing the results of the neurocognitive evaluation of 65 SH patients and 31 individuals without thyroid disease. Subclinical hypothyroidism was defined as at least two elevated serum TSH levels (> 4 microUI/ml) with normal serum free T4 levels (0.9-1.8 ng/dl). The participants underwent the following neuropsychological assessment: Buschkes Selective Reminding Procedure, Rey-Osterrieth Complex Figure Test, Warrington's Recognition Memory Test for Words and Faces, and the Vocabulary subtest of the WAIS-R. The groups were similar in regard to mean age, sex and educational level. No neuropsychological change was found in patients with SH when compared with euthyroid individuals. No difference was observed in the performance of the neuropsychological tests between both groups in regard to the functions studied.
ISSN:0004-2730
1677-9487
0004-2730
DOI:10.1590/s0004-27302007000400016