Use of amniotic membrane in trabeculectomy for the treatment of glaucoma: a pilot study

To compare the safety and efficacy of human preserved amniotic membrane (AM) in the trabeculectomy for treatment of primary open-angle glaucoma. A prospective, randomized clinical trial compared primary trabeculectomy with amniotic membrane (study group) and without amniotic membrane (control group)...

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Bibliographic Details
Published in:Arquivos brasileiros de oftalmologia 2006-06, Vol.69 (3), p.309-312
Main Authors: Eliezer, Ricardo Nunes, Kasahara, Niro, Caixeta-Umbelino, Cristiano, Pinheiro, Renato Kingleufus, Mandia, Jr, Carmo, Malta, Roberto Freire Santiago
Format: Article
Language:English
Subjects:
Amnion - transplantation
Case-Control Studies
Female
Follow-Up Studies
Glaucoma - surgery
Humans
Intraocular Pressure
Male
OPHTHALMOLOGY
Pilot Projects
Prospective Studies
Trabeculectomy - adverse effects
Trabeculectomy - methods
Treatment Outcome
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Summary:To compare the safety and efficacy of human preserved amniotic membrane (AM) in the trabeculectomy for treatment of primary open-angle glaucoma. A prospective, randomized clinical trial compared primary trabeculectomy with amniotic membrane (study group) and without amniotic membrane (control group) in the treatment of the glaucoma. Intraocular pressure (IOP), number of glaucoma medications and appearance of the bleb were compared between the two groups. Thirty-two patients divided into two groups of 16 patients were followed for a period of 12 months. The difference of the mean postoperative intraocular pressure between groups was not statistically significant (15.19 +/- 3.33 in the control group and 12.81 +/- 2.48 in the study group p=0.297) at one year follow-up. Postoperative number of medications decreased in both groups (p
ISSN:0004-2749
1678-2925
DOI:10.1590/S0004-27492006000300005