Nodular anterior scleritis associated with Berger's disease

A 45-year-old female patient presented with a complaint of right eye redness and pain for 7 days. She was under investigation for urinary abnormalities and reported a previous history of recurrent oral ulcers and ocular hyperemia in both eyes. Best-corrected visual acuity was 20/30 and 20/20 in the...

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Bibliographic Details
Published in:Arquivos brasileiros de oftalmologia 2021-01, Vol.84 (1), p.74-77
Main Authors: Constancio, Emanuelly Giovaneli, Alves, Débora Letícia Souza, Mello, Luiz Guilherme Marchesi, Silva, Lídia Balarini da, Saraiva, Fábio Petersen, Polido, Júlia, Cabral, Thiago
Format: Article
Language:English
Subjects:
Arthritis, Rheumatoid
Female
Glomerulonephritis, IGA
Humans
Immunosuppressive Agents - therapeutic use
Middle Aged
OPHTHALMOLOGY
Scleritis - diagnosis
Scleritis - drug therapy
Scleritis - etiology
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Summary:A 45-year-old female patient presented with a complaint of right eye redness and pain for 7 days. She was under investigation for urinary abnormalities and reported a previous history of recurrent oral ulcers and ocular hyperemia in both eyes. Best-corrected visual acuity was 20/30 and 20/20 in the right and left eyes, respectively. Slit-lamp biomicroscopy of the ocular surface of the right eye revealed nasal scleral hyperemia that persisted after instillation of topical phenylephrine 10%, reinforcing the diagnosis of anterior scleritis. Renal biopsy showed immunoglobulin A immune complexes and confirmed the suspected diagnosis of Berger's disease. Maintenance immunosuppressive therapy with azathioprine following a 6-month induction of remission with cyclophosphamide was necessary after pulse therapy with methylprednisolone. Scleritis is usually related to systemic autoimmune diseases, such as rheumatoid arthritis, and polyangiitis. Herein, we describe a rare case of unilateral anterior scleritis associated with Berger's disease.
ISSN:0004-2749
1678-2925
1678-2925
DOI:10.5935/0004-2749.20210011