Comparing the effects of serum GPER-1 and oxidant/antioxidant levels on retinopathy in patients with diabetes and healthy individuals: a pilot study

This study aimed to determine the effect of serum G receptor-mediated protein-1 levels on the development of retinopathy in patients with diabetes in comparison with healthy individuals. The study enrolled patients with diabetic retinopathy (Group 1), patients without diabetic retinopathy (Group 2),...

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Bibliographic Details
Published in:Arquivos brasileiros de oftalmologia 2022, Vol.87 (1), p.0311
Main Authors: Beyoğlu, Abdullah, Kurutaş, Ergül Belge, Karaküçük, Yalçın, Çömez, Ayşegül, Meşen, Ali
Format: Article
Language:English
Subjects:
Antioxidants - metabolism
Diabetes Mellitus
Diabetic Retinopathy - etiology
Estradiol
Humans
OPHTHALMOLOGY
Original
Oxidants
Oxidative Stress
Pilot Projects
Progesterone
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Summary:This study aimed to determine the effect of serum G receptor-mediated protein-1 levels on the development of retinopathy in patients with diabetes in comparison with healthy individuals. The study enrolled patients with diabetic retinopathy (Group 1), patients without diabetic retinopathy (Group 2), and healthy individuals (Group 3). Levels of serum progesterone, serum G receptor-mediated protein-1, estradiol, oxidant/antioxidants, and thyroid-releasing hormones were analyzed and compared among the groups. Post-hoc analysis was performed to compare the subgroups in which significant differences were found. Groups 1, 2, and 3 each included 40 patients. A significant difference was found among all groups in terms of serum G receptor-mediated protein-1, oxidant/antioxidant, and estradiol levels (p
ISSN:0004-2749
1678-2925
1678-2925
DOI:10.5935/0004-2749.2021-0311