Endoscopic follow-up of cyanoacrylate obliteration of gastric varices

Bleeding from gastric varices is a life-threatening condition. We report our experience with cyanoacrylate injection. Twenty three patients with portal hypertension and gastric varices underwent intra-variceal injection of a cyanoacrylate/lipiodol solution (1:1). Study endpoint was variceal oblitera...

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Bibliographic Details
Published in:Arquivos de gastroenterologia 2009-01, Vol.46 (1), p.81-84
Main Authors: Martins, Fernanda Prata, Macedo, Erika Pereira de, Paulo, Gustavo Andrade de, Nakao, Frank Shigueo, Ardengh, José Celso, Ferrari, Angelo Paulo
Format: Article
Language:English
Subjects:
Cyanoacrylates - adverse effects
Cyanoacrylates - therapeutic use
Esophageal and Gastric Varices - therapy
Female
Follow-Up Studies
GASTROENTEROLOGY & HEPATOLOGY
Gastrointestinal Hemorrhage - therapy
Hemostasis - drug effects
Hemostasis, Endoscopic
Humans
Male
Middle Aged
Recurrence
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Summary:Bleeding from gastric varices is a life-threatening condition. We report our experience with cyanoacrylate injection. Twenty three patients with portal hypertension and gastric varices underwent intra-variceal injection of a cyanoacrylate/lipiodol solution (1:1). Study endpoint was variceal obliteration. Mean follow-up was 25.3 months. Variceal obliteration was achieved in 87% of patients. Recurrence occurred in one patient (4.3%) and rebleeding in another case (4.3%). Mild abdominal pain was described in 13% of patients. Overall mortality was 21.7% and rebleeding related mortality rate was 4.3%. Our results confirm that cyanoacrylate injection is effective and safe to eradicate gastric varices.
ISSN:0004-2803
1678-4219
1678-4219
0004-2803
DOI:10.1590/S0004-28032009000100020