The frequency-amplitude gradient in the sleep EEG of children and its diagnostic significance

• Published in: Arquivos de neuro-psiquiatria 2007-06, Vol.65 (2A), p.206-211
• Main Authors: Aucélio, Carlos Nogueira, Niedermeyer, Ernst, Melo, Aurea Nogueira de
• Format: Article
• Language: English
• Subjects: Age Distribution; Age Factors; Brain - growth & development; Chi-Square Distribution; Child; Child, Preschool; Confidence Intervals; Electroencephalography; Humans; Infant; Nervous System Diseases - diagnosis; NEUROSCIENCES; PSYCHIATRY; Sleep - physiology
• ISSN: 0004-282X; 1678-4227; 0004-282X
• DOI: 10.1590/S0004-282X2007000200004

1014 EEGs of children in the 3-months to 12-years age group were obtained during sleep with the purpose of assessing the frequency and amplitude gradient (FAG) its absence thought to be an indicator of neurological disorder. FAG findings were divided into present/absent. The neurological findings were classified according to the presence (abnormal neurological finding-ANF) or absence (normal neurological finding-NNF) of neurological disorder. The association and significance between FAG and neurological findings was determined by prevalence ration (PR) and chi-square test (chi2). FAG showed a characteristic distributions of voltage output during non-REM sleep, stage II, in the 3-months to 5-years age group with NNF. The PR and the chi2 test demonstrated a strong association between FAG absent and ANF. FAG is an age-dependent EEG sleep parameter and absence of FAG in the 3-months to 5-years age group is highly suggestive of neurological disorder.