Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

• Published in: Arquivos de neuro-psiquiatria 2017-03, Vol.75 (3), p.153-159
• Main Authors: Benatto, Mariana Tedeschi, Florencio, Lidiane Lima, Carvalho, Gabriela Ferreira, Dach, Fabíola, Bigal, Marcelo Eduardo, Chaves, Thaís Cristina, Bevilaqua-Grossi, Débora
• Format: Article
• Language: English
• Subjects: Adult; Chronic Disease; Female; Humans; hyperalgesia; Hyperalgesia - etiology; Male; migraine disorders; Migraine Disorders - complications; NEUROSCIENCES; PSYCHIATRY; Severity of Illness Index; Skin Diseases - etiology; Socioeconomic Factors; Time Factors
• ISSN: 0004-282X; 1678-4227; 1678-4227; 0004-282X
• DOI: 10.1590/0004-282X20170015

ABSTRACT Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify subjects according to the presence and severity of cutaneous allodynia. Results Cutaneous allodynia was identified in 81.3% of the episodic migraine group and 92.5% of the chronic migraine group (p = 0.03). No increased association could be attributed to chronic migraine when adjusted by years with disease (PR = 1.12; 95%CI = 0.99 to 1.27; p = 0.06). The groups also did not differ in the severity of allodynia, and severe presentation was the most frequent. Discussion Both groups seemed to be similarly affected in the cephalic and extracephalic regions, with the same severity. Conclusion Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease.