Neurological complications in patients with SARS-CoV-2 infection: a systematic review

ABSTRACT Background: As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations. Objective: To review the literature on neurological complications of SARS-CoV-2 infection. Methods: Literature search performed following systematic reviews guide...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2020-05, Vol.78 (5), p.290-300
Main Authors: MUNHOZ, Renato Puppi, PEDROSO, José Luiz, NASCIMENTO, Fábio Augusto, ALMEIDA, Sergio Monteiro de, BARSOTTINI, Orlando Graziani Povoas, CARDOSO, Francisco Eduardo C, TEIVE, Hélio A Ghizoni
Format: Article
Language:English
Subjects:
Ageusia - complications
Brain Diseases - complications
Cerebrovascular diseases
Cerebrovascular Disorders - complications
Cerebrovascular Disorders - physiopathology
coronavirus infections
Coronavirus Infections - complications
Coronaviruses
COVID-19
encephalitis
Guillain-Barre syndrome
Guillain-Barre Syndrome - complications
guillain-barré syndrome
Humans
Myalgia
Myalgia - complications
Nervous System Diseases - complications
Nervous System Diseases - physiopathology
Neurological complications
neurology
NEUROSCIENCES
Olfaction Disorders - complications
Pandemics
Pneumonia, Viral - complications
PSYCHIATRY
Severe acute respiratory syndrome coronavirus 2
stroke
Vascular diseases
VIEW AND REVIEW
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Summary:ABSTRACT Background: As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations. Objective: To review the literature on neurological complications of SARS-CoV-2 infection. Methods: Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10 th , 2020. Results: A total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome. Conclusion: Recognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.
ISSN:0004-282X
1678-4227
1678-4227
DOI:10.1590/0004-282X20200051